Erythema multiforme is divided into major and minor forms and is now regarded as distinct from Stevens–Johnson syndrome (SJS) and toxic epidermal. dermal necrolysis, where erythema multiforme minor is the mildest type .. Gavaldá-Esteve C, Murillo-Cortés J, Poveda-Roda R. Eritema multiforme. Revisión y. Find out about erythema multiforme, a skin reaction that usually causes a rash for a few weeks.

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The rash is also more macular than in EM. Pathogenesis, clinical features, and diagnosis”.

Erythema multiforme – NHS

With epidermal involvement Eczematous contact dermatitis atopic dermatitis seborrheic dermatitis stasis dermatitis lichen simplex chronicus Darier’s disease glucagonoma syndrome langerhans cell histiocytosis lichen sclerosus pemphigus foliaceus Wiskott—Aldrich syndrome Zinc deficiency.

Erythema multiforme is not contagious. Retrieved 29 December The rash usually goes away in 1 to 2 weeks, but it can last as long as 4 weeks. Epidermal nekrolyse, toksiskToksisk epidermal nekrolyseLyells syndrom. Related links to external sites from Bing.

Erythema multiforme major can take up to 6 weeks to resolve. Symptoms include fever, malaise, sore throat, cough, vomiting, diarrhea, arthralgia, and myalgia.

The herpes infection usually precedes the skin eruption by 3—14 days. These images are a random sampling from a Bing multiformr on the term “Erythema Multifoeme Major. Infections that may lead to EM include: In erythema multiforme major, one or more mucous membranes are typically affected, most often the oral mucosa:. It is an immune complex hypersensitivity reaction usually caused by drugs e.

Complications of EM may include: The face, neck and trunk are common sites.


The blotches develop over a few days into round target often called “bulls-eye” shapes with red, pink, and pale rings.

Arch Dermatol ; More on this topic for: Pale edematous ring Outer: Episodic angioedema with eosinophilia Hereditary angioedema.

Freckles lentigo melasma nevus melanoma. The condition varies from a mild, self-limited rash E.

Erythema multiforme

In other projects Wikimedia Commons. This has been shown to be effective in placebo -controlled double blind studies. Clinical features, diagnosis, and treatment of erythema multiforme: Erythema multiforme majorerythema multiforme majorerythema multiforme major diagnosisErythema multiforme majErythema multiforme major NOSErythema Multiforme Major. These images are a random sampling from a Bing search on the term “Erythema Multiforme.

EM usually goes away on its own with or without treatment. A hypersensitivity reaction characterized by the sudden appearance of symmetrical cutaneous and mucocutaneous macular or papular lesions which evolve into lesions with bright red borders target lesions. This can be severe and require hospitalisation due to difficulty eating and drinking. But bacteria, fungi, and other viruses also can cause someone to develop the condition.

Although the full mechanism is not understood, it is in part due to a type Myltiforme hypersensitivity immune response, mediated by T lymphocytes. By using this multifomre, you dritema to the Terms of Use and Privacy Policy. Aphthous stomatitis oral candidiasis lichen planus leukoplakia pemphigus vulgaris mucous membrane pemphigoid cicatricial eritwma herpesvirus coxsackievirus syphilis systemic histoplasmosis squamous-cell carcinoma.

Back Links pages that link to this page. The histology of erythema multiforme is characteristic but not diagnostic.

Erythema Multiforme

Sometimes, a person may also get the rash after taking medicine. If you have any concerns with your skin or its treatment, see a dermatologist for advice. However, erythema multiforme may recur when the aciclovir is ceased. Mucosal lesions consist of swelling and redness with blister formation.


Symptoms of EM include: Epidemiology Most common in winter and early spring More common in adult women, but affects children of either gender equally Incidence U. There may be residual mottled skin discolouration. The use of systemic steroids for EM major remains controversial, as there is evidence both for and against treatment, and no randomized controlled trials have been done.

Erythema multiforme is a hypersensitivity reaction usually triggered by infections, most commonly herpes simplex virus HSV. Good hygiene and staying away from other people may help prevent secondary infections infections that occur from treating the first infection. Otolaryngology – Dermatology Pages. Systemic steroids have been suggested as adjuvant therapy based on their immunosuppressant effects.

A systemic, serious, and life-threatening disorder characterized by erythematous and necrotic lesions in the skin and mucous membranes that are associated with bullous detachment multiforem the epidermis.

Erythema multiforme EM Erythema multiforme minor of the hands note the blanching centers of the lesion Specialty Dermatology Erythema multiforme EM is a skin condition of unknown cause; it is a type of erythema possibly mediated by deposition of immune complexes mostly IgM -bound complexes in the superficial microvasculature of the skin and oral mucous membrane that usually follows an infection or drug exposure. A systemic, serious, and life-threatening disorder characterized by lesions in the skin and mucous membranes that may lead to necrosis.