Visit ChemicalBook To find more CALCIUM PANTETHEINE SULFONATE() information like chemical properties,Structure,melting point,boiling point,density. Category: cosmetic ingredient for skin and hair conditioning. Recommendation for calcium pantetheine sulfonate usage levels up to: not for fragrance use. Skin barrier function improved by hydroxyapatite and calcium pantetheine sulfonate combination. Gaudinat Marie-Hélène, L’Oréal Paris, Clichy, France;.

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As a blank test, the same operation as above was carried out using water instead of the above test solution or reference solution.

Access to the full text of this article requires a subscription. Its scientific backbone, combined with local consumer insights, results in innovative and transformational ingredients and concepts that help to build brands and benefit the end consumer. Pantetheine-s-sulfonic acid derivatives for promoting the growth of bi bifidum in infants. As to the safety of pantetheine-S-sulfonic acid, since it is a sulfonic acid derivative of pantethine, which is commercially available as a bifidus factor contained in an internal medicine, the safety of which has already been confirmed, and effectively used for a serum-lipid-reducing internal medicine which has no problem in its safety, pantetheine-S-sulfonic acid can be highly safely applied to skin without causing any toxicity as well as any side effects to skin such as stimulation and itching open patent No.

For comparison, pantethine solution of the same molar concentration as test solution B was prepared as reference solution B 0. You may choose a language below to continue to this industry or close this dialog above. In the following, experiments indicating the results of the pharmacological tests an in vitro test and actual clinical tests of the external preparation of this invention are shown. There is no restriction to the amount of the external preparation according to this invention to be applied to skin and the preparation should be either directly rubbed into the affected part or applied to gauze or the like before the gauze is applied on the affected part.

The results of the above experiment are shown in FIG.

calcium pantetheine sulfonate Ingredient Allergy Safety Information

However, UL assumes no responsibility or liability for the accuracy of the information contained on this website calium strongly encourages that upon final product or material selection information is validated with the manufacturer. Previous Article Clinical tolerance pantetheinee efficacy of capryloyl salicylic acid C8-LHA peel compared to a glycolic acid peel in subjects with fine lines and wrinkles.

After 1 ml of L-tyrosine solution 0. Here, each value represents difference between color differences between the non-pigmentation area and the pigmentation area before and after the treatment and a larger value indicates a greater improvemental effect.

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In contrast, pantetheine-S-sulfonic acid, as clearly seen from experiments described in the following, not only has an excellent effect in the treatment of pigmentation abnormalities but also can be prepared into an external preparation for application to skin at a far lower cost as compared to the above compounds because it is an odorless powder which can be handled easily. That is to say, pantetheine causes much inconvenience in handling due to its noncrystallinity and viscosity.

Pantetheine-S-sulfonic acid or its salt is a well-known compound represented by the following formula. Although further investigation is necessary in order to clarify detailed mechanisms of such effects, it is estimated that pantetheine-S-sulfonic acid has a powerful metabolism-accelerating effect.

After that, as the result of further investigation of pantothenic-acid-system compounds, it was newly found that pantetheine-S-sulfonic acid has a remarkable effect in the treatment of pigmentation abnormalities in the skin which is based on its tyrosinase-activity inhibiting effect and that it has an effect of improving the quality of skin such as rough skin through improvement and control of skin metabolism.

However, there are no experiences in which these compounds were used for external preparations for application to skin or suggesting the superior curative and preventive effect of said preparation on pigmentation. Total quantity was adjusted to g.

Conventionally, stress was placed on the prevention and treatment of the former troubles and minimal consideration was given to the latter troubles. If pabtetheine want to subscribe to this journal, see our rates. Besides it has a good treatment effect on suntans and is an excellent skin-quality improving preparation.

calcium pantetheine sulfonate

Year of fee payment: Actinic radiation protection by compositions comprising quinones and carbonyl containing compounds. In addition it has remarkable curative effects on burns, wounds, frostbite, ulcers, bed sores and the like. Access to the text HTML. Personal information regarding our website’s visitors, including their identity, is confidential.

Although there is no special restriction to the amounts of these components used in the preparation, it is usually preferred that these components be blended in a proportion of 0. However, in accordance with the recent changes in social conditions, the latter troubles also have come to be highlighted and studied.

Thus, the external preparation according to dalcium invention causes superior effects to diseases directly hindering the maintenance of health as well as diseases indirectly hindering the maintenance of health as previously mentioned.

Compositions for treatment of hyperpigmentation and methods for making and using such compositions. The results are shown in Table 2 and FIG.


From these results, it is seen that the external preparation of this invention has a notably higher pigmentation-curing effect as compared to the external preparation containing ascorbic acid. Skin troubles cxlcium those such as burns and wounds in which tissue is directly damaged, thereby causing a direct hindrance to the maintenance of health, and those involving pigmentation and coloration which cause problems in the appearance although not hindering the maintenance of health, thereby directly causing social impediments.

The following experiment was conducted on these test solutions and reference solution. A patch test was conducted beforehand to confirm the absence of any stimulating effect. However, it is hard to say that these materials are excellent due to their low stability, bad smell and inconvenience in handling as well as in terms of practical effect.

After compound 1 was impregnated with compound 2, the resulting mixture was added to solution prepared by dissolving the remaining components in purified water 6 while heating and stirring to obtain solution used as a plaster-type external preparation.

In addition, it was confirmed that pantetheine-S-sulfonic acid causes an excellent curative effect to wounds, burns and the like leading to a conviction that this compound can be very effectively used for an pantetbeine preparation for application to skin, thereby completing this invention.


Therefore, pantetheine is disadvantageous for an external preparation for application to skin, especially as a skin-whitening agent and can hardly be used for an external preparation for application to skin. Premium Body Care Unacceptable Ingredients.

Topical amino acid – vitamin complex compositions for pharmaceutical and cosmetic use. It is also one of the great advantages of the external preparation for application to skin according to this invention that it can widely be used in various forms panfetheine as powder, solution, emulsion, ointment, cataplasm and spray. This application is a division of application Ser.

It is said that a considerably large proportion of the middle-aged and elderly women are actually suffering from blemishes. Method and composition for controlled delivery of nascent oxygen from hydrogen peroxide source for skin treatment. For women especially, so-called blemishes are a serious problem in terms of both beauty and health. The content of such third party sites is not within our control, and we cannot and will not take responsibility for the information or content.