Malar J. Nov 26;17(1) doi: /sy. Aspidosperma pyrifolium, a medicinal plant from the Brazilian caatinga, displays a high. Aspidosperma pyrifolium Has Anti-Inflammatory Properties: An Experimental Study in Mice with Peritonitis Induced by Tityus serrulatus Venom or Carrageenan. Find technical and marketing information for lesser-used tropical timber species, LUS. Learn more on our Jitichuriqui (Aspidosperma pyrifolium) page.

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Then, the medium was replaced by serum-free medium for synchronizing the cell cycle in G0 phase. Finally, we revealed that the lungs of animals treated with rutin and aqueous extracts of A.

Scientific Name Aspidosperma pyrifolium Mart. Anti-snake venom activities of ethanolic extract of fruits of Piper longum L. This is an original study revealing the potential action of A.

In South America, this species is the most dangerous due to the high toxicity of its venom. Table 1 Anti-inflammatory activity of aqueous extract AE from the leaves of Aspidosperma pyrifolium and rutin against carrageenan-induced peritonitis model. Insulin-like effects of Bauhinia forficata aqueous extract upon Tityus serrulatus scorpion envenoming.

Investigation of cytotoxic, apoptosis-inducing, genotoxic and protective effects of the flavonoid rutin in HTC hepatic cells. Compounds 67 and 8 correspond to chlorogenic acid isomers, n -chlogenic, crypto-chlorogenic and iso-chlorogenic acid, respectively. Implications for inflammation, heart disease, and cancer. The effect of AE of A. The analysis shows one peak retention time: Detection at nm.

Flavonoidglycoside acids from flowers of Arnica montana und Arnica chamissonis. Aspidospermw It is reported to be high in luster. Furthermore, vascular ectasia and edema were also similar between the control group and the SAAV-treated group Figure aspidospfrma C.

Pyrivolium and Antivenom Lyophilized T.

Fact Sheet: Aspidosperma pyrifolium

Neutralizing effects of Mimosa tenuiflora extracts against inflammation caused by Tityus serrulatus scorpion venom. Tityus serrulatus venom increases vascular permeability in selected airway tissues in a mast cell-independent way. General Housing 10 – Silica in Timbers. The envenomation induced by scorpions of the genus Tityus spp. Saline solution Groups 1 and 2, i. Find articles by Silvana Maria Zucolotto.


Conclusions In conclusion, this approach demonstrated that aqueous extracts of A. Further studies are required to test the potential application of this extract and identified compound in the therapy of inflammatory conditions and of scorpion envenomation.

Briefly, mice were anesthetized and pretreated as described above. The leaves were washed, dried at room temperature, and milled.

On Asclepiadoideae plants, which are a subfamily of Apocynaceae, phytochemical studies verified the presence of phenolic compounds, as well as the flavonoids quercetin, rutin and isorhamnetin [ 2122 ].

Effects of aqueous extracts from the leaves of Aspidosperma pyrifolium on 3T3 cell lines at concentrations from 0.

Aspidosperma pyrifolium Images – Useful Tropical Plants

The flavonoid rutin occurs naturally in various plant species and is a potent antioxidant with a wide spectrum of applications and has been a subject of interest due to its various pharmacological activities, in particular its anti-inflammatory activity [ 232425262728 ]. It was used a split with the column eluent at a ratio of 7: Then, the exudates were centrifuged and total cell counts were performed. Rutin, one of the major compounds, and seven other phenolic derivatives, namely neo-chlorogenic acid, chlorogenic acid isomer n -chlogenic, crypto-chlorogenic and iso-chlorogenic acidisorhamnetin O -rutinoside, di- O -caffeoylquinic acid and isomer of the di- O -caffeoylquinic acid, were identified by LC-DAD-MS.

A step towards understanding the possible role of sodium channel modulators.

Aspidosperma pyrifolium

In this approach, we have investigated the ability of the aqueous extract from the leaves of Aspidosperma pyrifolium in reducing carrageenan-induced inflammation and the inflammation induced by Aspidospeerma. Introduction The scorpion genus Tityus is responsible for the majority of scorpion envenomation in Brazil, and, in particular, the species Tityus serrulatus Buthidae is the most common and harmful.


After six hours of envenomation induction, the mice were euthanized; 2 mL of cold sterile saline were injected in the peritoneal cavity and, after 30 s of gentle massaging, peritoneal fluid was collected. Flavonoids as medicinal agents: Medicinal uses, phytochemistry and pharmacology of Picralima nitida Apocynaceae in tropical diseases: Inflammatory cell infiltration, i.

The pathogenesis of this edema is very complex, therefore, envenomation by this species can be severe, and deaths are often caused by acute pulmonary edema [ 56 ]. Popular reports in aspidsoperma in the State of Rio Grande do Norte, Brazil, described that the old-aged-people used the species for the treatment of dizziness, urinary disorders, wound healing and inflammation. Envenomation was performed according to the procedure described by Pessini et al.

Texture This wood has a somewhat fine texture. Aspidosperma pyrifolium, also a medicinal plant, is used as a natural anti-inflammatory. The UV spectra of peaks unidentified in the chromatogram UV nm suggest the presence of phenolic acids before 25 min and flavonoids after the peak of rutin at 41 min. In turn, Figure 4 B reveals that the time of choice for euthanizing the pyrifollium was 6 h after envenomation, due to increased cell migration at that time-point. Support Center Support Center.

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Scientific Name Synonyms Macaglia pyrifolia Mart. The separation was performed using a Reverse Phase Luna C column 4. Figure 4 A shows that the dose of 7. The Handbook of Natural Flavonoids.

The present study was conducted pyfifolium evaluate the protective ability of aqueous extract from the leaves of Aspidosperma pyrifolium against inflammation induced by carrageenan and Tityus serrulatus scorpion venom.